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hippuric acid : ウィキペディア英語版
hippuric acid

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Hippuric acid (Gr. ''hippos'', horse, ''ouron'', urine) is a carboxylic acid found in the urine of horses and other herbivores. Hippuric acid crystallizes in rhombic prisms which are readily soluble in hot water, melt at 187 °C, and decompose at about 240 °C. High concentrations of hippuric acid may also indicate a toluene intoxication; however, scientists have called this correlation into question because there are other variables that influence levels of hippuric acid. When many aromatic compounds such as benzoic acid and toluene are taken internally, they are converted to hippuric acid by reaction with the amino acid, glycine.
==Synthesis==
A modern synthesis of hippuric acid involves the acylation of glycine with benzoyl chloride:
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